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 Biomedical Sciences exam 

Clinical Immunology and Immunohaematology
6BIOM003W

Case History Exam Section A July 2021

Patient HB is a non-sensitised, 45 year old male, who was diagnosed with kidney
failure caused by IgA nephropathy. 30 months ago, he received a renal transplant
from his wife, DB.

Initially the kidney functioned well, however over the last 6 months function has been
deteriorating and there are signs of rejection.

Blood group HLA-A HLA-B HLA-Cw HLA- DR HLA-DQ

Patient HB
(recipient)

O RhD
+ve A*29, A*02 B*44, B*7

Cw*16,
Cw*07

DRB1*11
DRB1*15

DQB1*0301
DQB1*06

Wife DB
(Donor)

O RhD
+ve A*03, A*02 B*27, B*44

Cw*02,
Cw*05

DRB1*11
DRB1*04

DQB1*0301
DQB1*0302